It is therefore important for FACS to publish a position statement on this matter to provide factual information to interested parties.
Tartrazine is a yellow food colourant which has been used for many years, however, it has been found to produce intolerant reactions in a few individuals. Some of the cases of adverse reactions have been related to its use in pharmaceutical preparations. Tartrazine intolerance has been estimated to affect between one and ten people in every ten thousand (between 0.01% and 0.1% of the population).
The adverse reactions which have been reported include urticaria (allergic skin rash), rhinitis (runny nose), asthma, purpura (purplish skin bruising) and systemic anaphylaxis (shock). The adverse reaction is more common in asthmatics and people who are sensitive to aspirin.
How Bad is the Intolerance?
The question of intolerance to Tartrazine should be seen against a background of food intolerance, allergy and hypersensitivity in general. The incidence of allergy and intolerance to foods containing milk, gluten, nuts and other allergens is very much higher than intolerance to foods containing Tartrazine and other food additives. In the same way as milk, gluten and nuts pose no threat to the vast majority of people, so Tartrazine containing products are entirely safe for the majority of the population. Those few who are intolerant are protected by South African food regulations which require that the Tartrazine in a product must be declared by name on the label, in the list of ingredients.
The use of Tartrazine has been reviewed by the Joint FAO/WHO (Food and Agriculture Organisation of the United Nations / World Health Organisation) Expert Committee on Food Additives and Acceptable Daily Intake of up to 7.5 mg/kg of body weight has been established. In the USA and the UK, estimates of the actual intake per head, carried out by the National Academy of Sciences in conjunction with the National Research Council and the FACC, are well below these levels. In the United Kingdom the Food Advisory Committee, in their final report on food colours (1987), does not take the view that the rare cases of allergy or hypersensitivity to certain food colours constitute valid grounds for restricting their use. The use of Tartrazine in fact is permitted in most countries including the United States of America, the United Kingdom, Canada, France, Germany, Japan and Holland.
The Southampton Study
A later study by the University of Southampton found an association between the consumption of some colourants which included Tartrazine and Attention Deficit and Hyperactivity Disorder in children (ADHD) and the UK therefore requires a warning statement to be printed on products containing Tartrazine and some other colourants. The European Food Safety Authority reviewed the UK research in 2008 and concluded that the Southampton study gives no basis for changing the acceptable daily intake (ADI) of food additives due to inconsistencies and the inability to attribute the ADHD effects observed to any additive in particular.
The FACS Message:
FACS appreciates that a small percent of the population could be sensitive to Tartrazine. It therefore supports not only product labelling but also any responsible effort that is made to provide scientifically correct information to the consumer about Tartrazine.
Prepared and updated for FACS by RTi (2016)